基于双pH/葡萄糖响应的白藜芦醇光热水凝胶促进糖尿病创面愈合高血糖、缺氧、慢性炎症与细菌感染多重因素共同作用，致使糖尿病创面极难愈合，各类病理因素协同抑制组织再生。病情严重时，上述并...

胶原网络重塑与细胞外基质力学性能研究新进展：开启关节软骨修复新时代关节软骨是一类高度特化的结缔组织，其细胞外基质（ECM）具备层级化有序结构，可为关节生理活动提供所需力学缓冲能力。该...

基于微纳米水凝胶微球内外双重介导生物正交活化，精准清除胞内耐甲氧西林金黄色葡萄球菌针对胞内耐甲氧西林金黄色葡萄球菌（MRSA）的传统大剂量抗生素疗法疗效极差，且感染复发率居高不下。声动...

    碘-131标记双免疫检查点抑制剂：改善肿瘤微环境以提升抗肿瘤疗效双特异性免疫检查点抑制剂（ICIs）可靶向多种免疫检查点分子，具备成为放射免疫治疗（RIT）载体的良好应用前景。本研究采...

新型C₂对称手性双功能伯胺催化剂：设计、合成及其在不对称羟醛反应中的应用α-支链醛与α-羰基醛的羟醛反应是一类重要的有机合成反应，可直接构建含有季碳中心的高价值手性1,4-二羰基化合物。...

铁掺杂相变纳米液滴用于肿瘤协同光热治疗及饥饿增强型铁死亡疗法 铁死亡疗法借助芬顿反应杀伤癌细胞，已成为一种极具潜力的抗肿瘤策略：该反应中，二价铁离子可催化过氧化氢分解生成羟基自由基...

透明质酸修饰壳聚糖纳米颗粒靶向递送剪切力响应型叉头框蛋白C1基因，通过Hippo-YAP信号通路抑制动脉粥样硬化 已有研究证实，血流产生的剪切应力主要通过调控内皮细胞功能、炎症反应及氧化应激，...

酚类金属修饰共价有机聚合物纳米酶用于肿瘤微环境响应型光热增效活性氧疗法 本研究制备了一种经金属-酚网络（MPN）修饰的共价有机聚合物（COP）基纳米酶（COP@MPN）。该复合纳米酶具备更优异的...

单模微波辐照下条带状赤铁矿的断裂机理：基于温度与裂纹分布规律的研究 微波辅助破碎技术可实现条带状铁矿石的连续开采。为探明铁矿石在单模微波辐照下的响应特征，揭示条带构造作用下矿石的断...

肥大细胞在脑部疾病中的作用及作用机制 肥大细胞是天然免疫系统中关键的效应细胞，主要分布于皮肤、呼吸道、胃肠道、泌尿生殖道以及脑组织中。生理状态下，脑内固有肥大细胞可分泌多种神经调节...

纳米气泡曝气可加快粪污废水无害化处理进程、提升氮素留存率，同时减少温室气体排放。 纳米气泡曝气可显著提升水体溶解氧含量与羟基自由基生成量，强化化学需氧量、五日生化需氧量及大肠杆菌的...

宽温区表现出超顺磁特性的二维氯化钒纳米片 超顺磁材料在高密度磁存储、磁传感器及生物医学成像领域具有关键作用。本文在常温环境下，将还原氧化石墨烯置于不饱和三氯化钒溶液中，制备出二维氯...

ZK60镁合金表面构建BMP2@聚多巴胺-层状双金属氢氧化物功能涂层：兼具优异耐腐蚀性与骨缺损修复促再生效果 镁合金作为可降解骨科植入材料具备显著优势，但该材料在生理环境中降解过快，且骨整合...

用于高性能氟离子电池的弱溶剂化电解液设计与合成 氟离子电池的能量密度可达锂离子电池的10倍，同时安全性更优，是极具发展前景的新一代储能器件。但传统电解液电化学稳定窗口窄、离子电导率低...

双Z型异质结体系下光催化析氢与抗生素降解协同耦合反应 光催化技术现已成为环境修复（包括污染物降解）与太阳能转化（如制氢、二氧化碳还原）领域的关键技术。光催化技术的性能效率取决于价带空...

水泡性口炎病毒-基孔肯雅病毒可在黑色素瘤模型中通过诱导细胞焦亡激活抗肿瘤免疫 黑色素瘤治疗难度大、复发率高且具备侵袭转移能力，是恶性程度最高的皮肤肿瘤。水疱性口炎病毒可作为溶瘤病毒载...

二维二硫化钼基多模态肿瘤诊疗一体化的最新研究进展 癌症领域的研究不断取得新突破，各类新型纳米材料应运而生，助力优化肿瘤诊断与治疗方案。二维二硫化钼材料具备优异性能，在生物医学领域拥...

依托试验研究、数据分析与健康状态评估，实现退役动力电池从报废闲置到储能复用的价值重塑 退役动力电池应用于电网储能领域兼具生态效益与经济效益。本文聚焦面向电网储能场景的退役电池健康状...

运动预防肌少症的肠-肌肉轴作用机制 肌少症是一种全身性骨骼肌疾病，主要表现为肌肉量与肌肉力量同步下降，其患病率随年龄增长而升高。肌少症会降低机体运动能力，引发骨折等跌倒相关损伤，降低...

人工智能在食品品质与安全指标定量分析中的最新研究进展综述 食品质量与安全关乎每个人的日常生活与身体健康。随着分析科学领域的飞速发展，行业对食品质量与安全的直观、精准、快速管控需求日...

  Mechanism of confinement enhancing enzyme intrinsic activity Enzymatic catalysis within surface- and volume-confined environments is common in biological cells or industrial...

  无外加电解质条件下电化学促进喹喔啉-2(1H)-酮和苄氯的脱氯苄基化反应★ 有机电化学合成利用电能驱动合成反应的进行, 无需使用传统的化学氧化还原试剂, 具有反应条件温和、反应易调控、...

  Autonomous Soft Robots: Self-regulation, Self-sustained, and Recovery Strategies Autonomous, adaptable, and multimodal locomotion capabilities, which are crucial for the adv...

  Innovating transcranial magnetic stimulation treatment for post-traumatic stress disorder: Zapping away the bad memory Post-traumatic stress disorder (PTSD) is a debilitatin...

Nitrifier Assemblages and Dynamics in Secondary Water Supply Systems: Predominance of Comammox Nitrospira in Tank Biofilm and Sediment Nitrifiers in chloraminated drinking water di...

A drug-loaded composite coating to improve osteogenic and antibacterial properties of Zn–1Mg porous scaffolds as biodegradable bone implants Zinc (Zn) alloy porous scaffolds produ...

Self-Growing Organic Materials The growth of living systems is ubiquitous. Living organisms can continually update their sizes, shapes, and properties to meet various environmental...

Design, Synthesis, and Antifungal Activity of Polyacetylenic Alcohol Derivatives and Stereoisomers against Phytopathogenic Fungi Falcarindiol is active against phytopathogenic fung...

Nanoselenium Alleviates Cadmium-Induced Cerebral Injury via Regulating Cerebral Metal Transporters and Metal-Regulatory Transcription Factor Cadmium (Cd) is a hazardous environment...

The Oxysterol Receptor EBI2 Links Innate and Adaptive Immunity to Limit IFN Response and Systemic Lupus Erythematosus (Adv. Sci. 27/2023) In article number 2207108, Nan Shen, Hongy...

Cover Feature: Oxygen Vacancy Promoted Generation of Monatomic Oxygen Anion over Ni2+-Doped MgO for Efficient Glycolysis of Waste PET (ChemSusChem 9/2023) Cover Feature: Oxygen Vac...

Electrospun nanofibrous membranes meet antibacterial nanomaterials: From preparation strategies to biomedical applications Electrospun nanofibrous membranes (eNFMs) have been exten...

 

MS-CADNet: A Multi-Scale Context Attention Network for Efficient Object Detection in UAV Imagery With the rapid advancement of unmanned aerial vehicle (UAV) technology, there is a ...

  High-frequency enhanced ultrafast compressed active photography Abstract Single-shot ultrafast compressed imaging (UCI) is an effective tool for studying ultrafast dynamics ...

Self-Adaptive Quantum Kernel Principal Component Analysis for Compact Readout of Chemiresistive Sensor Arrays (Adv. Sci. 15/2025) In article number 2411573, Zeheng Wang, Timothy va...

Van der Waals Integrated LiNbO3/WS2 for High-Performance UV–Vis–NIR Photodetection (Laser Photonics Rev. 17(10)/2023) Van der Waals Integrated LiNbO3/WS2 for High-Performance UV...

Hormetic Effect of Pyroligneous Acids on Conjugative Transfer of Plasmid-mediated Multi-antibiotic Resistance Genes within Bacterial Genus Spread of antibiotic resistance genes (AR...

What if we could stop chronic pain before it starts? (Lai Lab) Since 2004, UT Health San Antonio, Greehey Children’s Cancer Research Institute’s (Greehey CCRI) mission has been t...

Engineered bacteria for near-infrared light-inducible expression of cancer therapeutics Bacteria-based therapies hold great promise for cancer treatment due to their selective tumo...

   Spectral-Based Machine Learning Enables Rapid and Large-Scale Adsorption Capacity Prediction of Heavy Metals in Soil Accurate and large-scale estimation of the soil adsorption...

Experimental Investigation of Hydrate Production via Deep Depressurization Using a Large-Scale Laboratory Reactor Experimentally investigating hydrate formation and gas recovery in...

磁悬浮飞行隧道移动噪声源的识别与鉴定方法 磁悬浮飞行风洞是一种基于“物体移动与风静”原理的新型概念性空气动力学测试设施，这对声学测试中移动声源的定位和评估提出了新的挑战。为此，本文...

UV Irradiation-Induced Cyclic-to-Linear Topological Changes of a Light/pH Dual-Sensitive Cyclic Copolymer for Enhanced Drug Delivery Cyclic polymers with cleavable backbones trigge...

Panoramic View of Interface-Related Thermo-oxidative Aging of Carbon Fiber-Reinforced Epoxy Composites The thermo-oxidative aging mechanism of carbon fiber-reinforced epoxy (CF/EP)...

Cover Picture: Mechanochemical Synthesis of Stimuli Responsive Microgels (Angew. Chem. Int. Ed. 34/2023) Mechanochemical approaches are widely used for the efficient, solvent-free ...

Tracking the Changes of DOM Composition, Transformation, and Cycling Mechanism Triggered by the Priming Effect: Insights from Incubation Experiments The priming effect (PE) is reco...

A 19% efficient and stable organic photovoltaic device enabled by a guest nonfullerene acceptor with fibril-like morphology† A nonfullerene acceptor, isoIDITC, capable of exhibiti...

Cs3Cu2I5 Single Crystal for Efficient Direct X-Ray Detection (Advanced Optical Materials 19/2023) In article number 2300247, Laishun Qin, Hongsheng Shi, Yanliang Liu, Xue-Feng Yu, ...

The Role of Reactive Oxygen Species in Alzheimer's Disease: From Mechanism to Biomaterials Therapy (Adv. Healthcare Mater. 29/2024) The dragon represents the mechanisms of oxidativ...