具有抗癌活性的氮杂螺环四-/五环骨架的化学选择性、区域选择性及非对映选择性合成 本文报道了一种高效、高选择性构建氮杂螺环多环骨架的合成方法，该方法表现出优异的化学选择性、区域选择性及...

Tracking the Changes of DOM Composition, Transformation, and Cycling Mechanism Triggered by the Priming Effect: Insights from Incubation Experiments The priming effect (PE) is reco...

Novel Muscle-Homing Peptide FGF1 Conjugate Based on AlphaFold for Type 2 Diabetes Mellitus Drugs for metabolic diseases usually require systemic administration and act on multiple ...

一种新型共连续 Si-Zr 杂化酚醛气凝胶复合材料，通过海岛状陶瓷结构在高温下实现优异的抗氧化消融性能 轻质酚醛基复合材料在未来航空航天飞行器的烧蚀热防护材料中具有很大的潜力，混合改性被认...

LC3B Binds to the Autophagy Protease ATG4b with High Affinity Using a Bipartite Interface Autophagy is a catabolic cellular process in which unwanted proteins and organelles are de...

Nanoselenium Alleviates Cadmium-Induced Cerebral Injury via Regulating Cerebral Metal Transporters and Metal-Regulatory Transcription Factor Cadmium (Cd) is a hazardous environment...

单宁酸促进葡萄糖氧化酶在钛表面的沉积以减轻持续的细菌感染 在货号中2201506、En-Tang Kang、Li-Qun Xu 及其同事为 H 构建了单宁/葡萄糖氧化酶平台2O2使用简单的浸泡方法，通过受茶染色启发的...

近年来，化学家设计了数百种分子，这些分子可能在能量储存的流动电池中非常有用。来自荷兰埃因霍温的DIFFER研究人员想象，如果这些分子的性质能快速且轻松地被数据库检索，那将是多么美好。然而...

增强 H2-驱动型 CO2通过降低液膜阻力和异质性，在双向流潮汐生物反应器中实现生物甲烷化性能 本研究提出了一种旨在提高 H2-驱动型 CO2生物甲烷化。生物反应器在浸入营养液和暴露于 H 之间交替使...

 

Alteration of Mitochondrial Lipidome and Its Potential Effect on Apoptosis, Mitochondrial Reactive Oxygen Species Production, and Muscle Oxidation in Beef during Early Postmortem L...

  本动画聚焦于 210+N 全球超级工厂 的整体体系展示，系统呈现工厂内部的核心设施布局、生产流程与协同运作方式。 由制作老师 赵紫阳老师 负责完成，通过清晰的结构拆解与流程可视化表达，...

 

介孔 CdS 纳米颗粒的合成和光催化性能 介孔纳米材料因其比表面积大、电荷转移距离短而被认为是先进的功能材料。在此，使用原位模板法制备了具有介孔结构的 CdS 纳米颗粒 （CdS MNPs）。CdS/Cd-C...

  可注射缓释丹参素钠载药纳米粒水凝胶靶向巨噬细胞改善心肌微环境用于心肌梗死治疗 心肌梗死（MI）可引发心肌细胞坏死、炎症反应、纤维化及心室重构，最终导致心力衰竭。针对这一问题，本...

新发现的介导肿瘤发生和肿瘤进展的机制：circRNA 编码的蛋白质 由环状 RNA （circRNA） 中的内部核糖体进入位点 （IRES） 介导的不依赖帽的翻译产生的蛋白质在肿瘤进展中起重要作用。迄今为止，...

   

The Oxysterol Receptor EBI2 Links Innate and Adaptive Immunity to Limit IFN Response and Systemic Lupus Erythematosus (Adv. Sci. 27/2023) In article number 2207108, Nan Shen, Hongy...

用于下一代光电器件的高柔性和耐酸碱 TiN 纳米网格透明电极 透明电极对于光电器件至关重要，但其发展受到现有材料（如氧化铟锡 （ITO） 和较新替代品）的局限性的限制。所有这些都面临着在恶劣...

Engineered bacteria for near-infrared light-inducible expression of cancer therapeutics Bacteria-based therapies hold great promise for cancer treatment due to their selective tumo...

Cs3Cu2I5 Single Crystal for Efficient Direct X-Ray Detection (Advanced Optical Materials 19/2023) In article number 2300247, Laishun Qin, Hongsheng Shi, Yanliang Liu, Xue-Feng Yu, ...

Influence of Carbonate Speciation on Hydrated Electron Treatment Processes Advanced reduction processes (ARPs) that generate hydrated electrons (eaq–; e.g., UV-sulfite) have emerg...

  Ablation of Tas1r1 Reduces Lipid Accumulation Through Reducing the de Novo Lipid Synthesis and Improving Lipid Catabolism in Mice Amino acid sensing plays an important role ...

Simultaneous Detection of Citric Acid and Oxalic Acid Based on Dual Spectrum and Biomimetic Peroxidase for Urolithiasis Screening with a Fully Automatic Urine Analyzer (Small 9/202...

 

通过实验、数据分析与健康状态评估，让退役电池重获新生、焕发效能 退役电动汽车电池在电网储能中的再利用具有环境与经济双重效益。本研究聚焦于电网储能场景下退役电池的健康监测算法，通过15...

Cover Picture: Mechanochemical Synthesis of Stimuli Responsive Microgels (Angew. Chem. Int. Ed. 34/2023) Mechanochemical approaches are widely used for the efficient, solvent-free ...

磁悬浮飞行隧道移动噪声源的识别与鉴定方法 磁悬浮飞行风洞是一种基于“物体移动与风静”原理的新型概念性空气动力学测试设施，这对声学测试中移动声源的定位和评估提出了新的挑战。为此，本文...

Design, Synthesis, and Antifungal Activity of Polyacetylenic Alcohol Derivatives and Stereoisomers against Phytopathogenic Fungi Falcarindiol is active against phytopathogenic fung...

在数字微流控平台上通过多重核酸检测快速鉴定细菌，以加强对感染的临床干预 细菌感染通常会导致严重的健康后果，因为它们能够渗透到多个解剖部位，包括血液、呼吸道和消化道，从而带来重大的诊...

  Autonomous Soft Robots: Self-regulation, Self-sustained, and Recovery Strategies Autonomous, adaptable, and multimodal locomotion capabilities, which are crucial for the adv...

 

Isotope Evidence for Rice Accumulation of Newly Deposited and Soil Legacy Cadmium: A Three-Year Field Study Biogeochemical processes of atmospherically deposited cadmium (Cd) in so...

D-A 型 NIR-II 有机分子：增强荧光亮度的策略及其在 NIR-II 荧光成像导航光热疗法中的应用 在文章中2201158由 Peng Wang、Pengfei Sun、Min Ji 及其同事系统介绍了 D-A 型小分子和共轭聚合物增...

介孔 CdS 纳米颗粒的合成和光催化性能 介孔纳米材料因其比表面积大、电荷转移距离短而被认为是先进的功能材料。在此，使用原位模板法制备了具有介孔结构的 CdS 纳米颗粒 （CdS MNPs）。CdS/Cd-C...

Nitrifier Assemblages and Dynamics in Secondary Water Supply Systems: Predominance of Comammox Nitrospira in Tank Biofilm and Sediment Nitrifiers in chloraminated drinking water di...

一种变色仿生材料，与植被叶子的光谱特性非常相似 多光谱/高光谱技术可以通过物体和植被之间细微的光谱差异轻松检测植被中的人造物体，而强大的侦察能力增加了对与植被光谱非常相似的伪装材料的...

Foundation 模型驱动的多模态预后预测高级别浆液性卵巢癌初次手术患者 高级别浆液性卵巢癌 （HGSOC） 在预后预测方面存在挑战。本研究旨在开发一种通用基础模型驱动的多模态模型 （FoMu model）...

Hormetic Effect of Pyroligneous Acids on Conjugative Transfer of Plasmid-mediated Multi-antibiotic Resistance Genes within Bacterial Genus Spread of antibiotic resistance genes (AR...

  High-frequency enhanced ultrafast compressed active photography Abstract Single-shot ultrafast compressed imaging (UCI) is an effective tool for studying ultrafast dynamics ...

Panoramic View of Interface-Related Thermo-oxidative Aging of Carbon Fiber-Reinforced Epoxy Composites The thermo-oxidative aging mechanism of carbon fiber-reinforced epoxy (CF/EP)...

星载单光子计数成像系统仿真技术研究 封面展示了低轨卫星单光子激光雷达成像过程，重点突出了偏振滤波光学系统、单光子雪崩光电探测器阵列、基于泊松滤波理论的光子计数技术等关键环节。通过调...

开放世界测试时训练模型的鲁棒性研究 如何让深度学习模型以低延迟适配未见过的目标领域，这一需求推动了对测试时训练/适配（TTT/TTA）的研究。然而，在开放世界环境中部署TTT/TTA面临挑战，核心...

Cover Feature: Oxygen Vacancy Promoted Generation of Monatomic Oxygen Anion over Ni2+-Doped MgO for Efficient Glycolysis of Waste PET (ChemSusChem 9/2023) Cover Feature: Oxygen Vac...

The Role of Reactive Oxygen Species in Alzheimer's Disease: From Mechanism to Biomaterials Therapy (Adv. Healthcare Mater. 29/2024) The dragon represents the mechanisms of oxidativ...

A drug-loaded composite coating to improve osteogenic and antibacterial properties of Zn–1Mg porous scaffolds as biodegradable bone implants Zinc (Zn) alloy porous scaffolds produ...

UV Irradiation-Induced Cyclic-to-Linear Topological Changes of a Light/pH Dual-Sensitive Cyclic Copolymer for Enhanced Drug Delivery Cyclic polymers with cleavable backbones trigge...